One of the challenges is the current lack of a freely available, comprehensive collection of aging-related biological pathways and encyclopedia of aging knowledge. Nevertheless, it faces several challenges, and the growth will need direction. To offset the burden of this shift, scientific knowledge and innovation will become increasingly crucial, and anti-aging and disease prevention strategies will become national and international priorities. As the body of knowledge in aging research is rapidly increasing, an open visual encyclopedia of aging processes will be useful to both the new entrants and experts in the field.Īs the world population is rapidly aging, the prevalence of aging-related diseases and the demand for expensive, long term health care is also rising ( 1– 4). Building on an initial content base constructed by a team of experts from peer-reviewed literature, users can integrate new data into biological pathway diagrams for a visible, intuitive, top-down framework of aging processes that fosters knowledge-building and collaboration. Aging Chart ( ) is a new, community-curated collection of aging pathways and knowledge that provides a platform for rapid exploratory analysis. Age-related processes occur on molecular, cellular, tissue, organ, system, organismal and even psychological levels, trigger the onset of multiple debilitating diseases and lead to a loss of function, and there is a need for a unified knowledge repository designed to track, analyze and visualize the cause and effect relationships and interactions between the many elements and processes on all levels. Aging research is a multi-disciplinary field encompassing knowledge from many areas of basic, applied and clinical research.
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